Detail Research Data


Data Resident (PPDS)
Research Title Gastric Residual Volume Correlation With Levels of blood Lactate, ScvO2 and P (cva) CO2 in resuscitated severe sepsis and septic shock patient at ICU RSCM.
Kaji Etik Pass Number
Kaji Etik Pass Date 00 00 0000
Focus Others (-)
Principal Investigator M. Azhari Taufik
Pembimbing 1 Dita Aditianingsih
Pembimbing 2 Yohanes W George
Pembimbing 3 dr. Luciana B. Sutanto MS, SpGK
Departement Anesthesiology
Category Other
Research Date 00 00 0000
Research Object Manusia
Fund Source
Level Penelitian Resident (PPDS)
Abstract

Background: Severe sepsis and septic shock is closely associated with a decreasing
of cardiovascular system function that can develops to shock.
Based EGDT protocol
using systemic microcirculation parameters, for example the levels of lactate, ScvO2
and P (cv-a) CO2 may reduce mortality compared with a simple parameters. Patients
with normal systemic perfusion, still allowing regional hypoperfusion. Splanchnic
region, is one of the earliest organ hypoperfusion were not detected by the systemic
hemodynamic parameters. This study aims to assess splanchnic hypoperfusion with a
simple method that gastric residual volume by looking the relationship with systemic
microcirculation parameters, that the levels of lactate, ScvO2 and the value of P (cva)
CO2.
Methods: This study was a cross-sectional study to test the correlation between
gastric residual volume and levels of lactate, ScvO2 and the value of P (cv-a) CO2 at
0, 8 and 24 taken consecutively in patients with postresusitation of severe sepsis and
septic shock in ICU RSCM in February 2014 to April 2014. The mortality rate seen
during 28 days later.
Results: A total of 53 subjects enrolled in this study. There was no significant
correlation between gastric residual volume and levels of lactate, ScvO2 and the
value of P (cv-a) CO2 at 0, 8 and 24 hour. Obtained a weak correlation between
gastric residual volume and value of P (cv-a) CO2 at-0 (r: 0.37, p: 0.006). The
mortality rate was 58.4% 28 days, most of the patients died in the ICU.
Conclusions: There was no significant correlation between the rate of gastric
residual volume lactate, ScvO2 and the P (cv-a) CO2 at the 0, 8 th and 24 th.
Keywords: Severe sepsis, Septic shock, Splanchnic hypoperfusion, Gastric residual
volume, Blood lactate levels, ScvO2, P (cv-a) CO2.